Insights
PLLACUBE Clinical Before & After Results – Proven Improvements in Pores, Texture, Hydration & Skin Tone
Clinical Before & After Results with PLLACUBE Documented improvements in skin pores, texture, hydration, and brightness after 3 weeks of treatment. All images captured under standardized, controlled lighting as part of a GCP-compliant clinical study. Skin Pores (Volume) Measured by Antera 3D – Average pore volume reduced after 3 weeks of PLLACUBE application, improving overall skin smoothness. Before After 3 Weeks Skin Texture (Ra, μm) Measured by Antera 3D – Significant reduction in surface roughness (Ra), creating a smoother, refined skin texture. Before After 3 Weeks Epidermal Hydration Measured by Epsilon E100 – Visible increase in skin moisture levels, contributing to plumpness and a healthy glow. Before After 3 Weeks Skin Tone / Brightness (L*) Measured by Mark-Vu Colorimeter – Improved L* value indicates brighter, more even skin tone after PLLACUBE use. Before After 3 Weeks
Learn more
PLLACUBE: 0.00 Irritation Index & Clinically Proven Skin Improvements in 3 Weeks
0.00 Irritation Index — Rated ‘Excellent’ Dermatologist‑evaluated 24‑hour primary irritation test on clinically confirmed sensitive skin. Test Item Inspection Standard Result Irritation Evaluation Suitability test for sensitive skin (primary irritation) GCP & MFDS‑approved protocol 0.00 No irritation (Excellent) Test Method: Test site wiped with 70% ethanol, product loaded in a Finn Chamber® and attached for 24 hours. Irritation assessed at 30 min & 24 hrs post‑removal. Test Location: Human Co., Ltd. Skin Clinical Trial Center, Korea. Participants: 33 adults with clinically confirmed sensitive skin. Clinically Measured Results at 3 Weeks Single‑arm evaluation (n=30). All changes significant vs. baseline (p<0.001). Deep Hydration (TDC) +14.19% Moisturemeter D Skin Brightness (L*) +0.78% Mark‑Vu Colorimeter Skin Texture (Ra, μm) −7.58% Antera 3D Dermis (Deep) Elasticity +2.46% Cutometer R2 • 8 mm Epidermal Elasticity +3.82% Cutometer R2 • 2 mm Skin Pores (Volume) −13.04% Antera 3D Methods: Moisturemeter D (TDC); Mark‑Vu Colorimeter (L*); Antera 3D (Ra, mean pore volume); Cutometer dual MPA 580 R2 (2 mm & 8 mm). Human Co., Ltd. Skin Clinical Trial Center (Korea). Three‑week application; results mean ± SD; all p<0.001 vs. baseline.
Learn more
How PLLACUBE Delivers Results with MTS, Laser & Topical Use
Discover how PLLACUBE adapts to microneedling, laser, and more. Clinically proven to improve hydration, elasticity, and pore appearance in just 3 weeks.
Learn more
What Is PLLACUBE? Meet the Science-Driven Cosmetic Skin Booster for Professional Use
Introduction – What Is PLLACUBE? PLLACUBE is an advanced all-in-one cosmetic skin booster developed for professional use in medspas, aesthetic clinics, and skin care studios. It features a science-backed formulation designed to support hydration, radiance, and skin conditioning — all while leveraging the patented INCUBE™ technology developed by Labincube Co., Ltd. in South Korea. Backed by Material Science: The INCUBE™ Innovation Founded in 2021, Labincube specializes in porous carrier materials and has developed a proprietary technology called INCUBE™ — based on Metal-Organic Frameworks (MOFs). This material helps stabilize active cosmetic ingredients and supports consistent formulation performance by controlling the release and integrity of ingredients such as Vitamin C and Glutathione. In other words, INCUBE™ acts as a delivery-support material that ensures cosmetic actives remain well-dispersed and stable until applied. PLLACUBE Skin Booster – Cosmetic Actives, Balanced Formulation There are two topical cosmetic products in the PLLACUBE lineup: PLLACUBE Original Poly-L-Lactic Acid (PLLA): Supports the appearance of skin elasticity and firmness PDRN (Sodium DNA): Conditions and hydrates skin for a revitalized appearance Vitamin C (Ethyl Ascorbyl Ether): Offers antioxidant support for a radiant-looking complexion Glutathione: Enhances skin brightness and overall glow Sodium Hyaluronate (HA): Helps maintain skin moisture Houttuynia Cordata Extract (Plant-based Exosome): Known for calming and conditioning effects PLLACUBE PiNk VoL. PLLA, PN (Polydeoxyribonucleotide), Vitamin C, Glutathione, and HA for similar cosmetic skin conditioning effects PLLACUBE Cosmetic Use & Professional Application Intended for professional use in cosmetic skin treatments Global Expansion & Industry Recognition PLLACUBE has been showcased at major industry events including: Cosmoprof Bologna (Italy) KIMES Seoul (International Medical Equipment Exhibition) These events spotlight innovation in cosmetic technology and skincare — and PLLACUBE has attracted attention for its ingredient integrity and cosmetic formulation science. Now Available in Canada Derma Essence Canada Ltd. is the official distributor of PLLACUBE products across Canada and North America. We are committed to providing professional-use, compliant cosmetic solutions backed by science, formulation stability, and visual performance. Interested in Offering PLLACUBE at Your Clinic? Contact us at info@derma-essence.com or explore our professional-use collection at www.derma-essence.com
Learn more