NEXT-GEN SKINBOOSTER FORMULATION POWERED BY INCUBE™
The Future of Skin Regeneration — Arrives in North America
Introducing PLLACUBE®, Korea’s pioneering 5th-generation skinbooster — a synergistic formula combining PLLA, PDRN, Vitamin C, Glutathione, Houttuynia Cordata Extract, and Hyaluronic Acid, powered by InCube™ Technology for maximum stability and efficacy.
PLLA · PDRN · Glutathione · Vitamin C · Plant-Derived Exosomes
🔗 Developed by Lab InCube Co., Ltd. — a Korean biomaterial R&D company specializing in advanced material science and applied biotechnology.
What is PLLACUBE?
PLLACUBE® is a next-generation skinbooster that combines Poly-L-Lactic Acid (PLLA) with PDRN, Vitamin C, Glutathione, Houttuynia Cordata Extract, and Hyaluronic Acid — formulated to deliver both regenerative and brightening effects.
Among these ingredients, Vitamin C and Glutathione, which are vulnerable to oxidation and degradation, are stabilized through the InCube™ Protection Platform developed by Lab InCube Co., Ltd. .
- InCube™–C → Selective Ingredient Encapsulation
- InCube™–P → Environmental Protection System
- InCube™–R → Optimized Ingredient Release
Backed by a patented proprietary process (Patent No. 10-2488551), InCube™ provides an advanced material protection and controlled-release platform, ensuring maximum ingredient stability, efficacy, and performance in every vial of PLLACUBE®.
Learn More about LabInCube →Key Ingredients of PLLACUBE® Original — All in One
Formulated with PLLA, PDRN, Vitamin C, Glutathione, Houttuynia Cordata Extract,
and Hyaluronic Acid, PLLACUBE® Original offers a next-generation approach to professional skin revitalization.
This synergistic combination is designed to help improve the appearance of firmness, clarity, and overall skin quality —
supporting a smoother and more radiant complexion after treatment.
Among the actives, Vitamin C and Glutathione are safeguarded through the
InCube™ stabilization platform, which helps maintain ingredient freshness and minimize oxidation during formulation,
ensuring consistent quality in every vial.
InCube™ C·P·R Technology (Capsulation · Protection · Release) is a patented biomaterial stabilization system from Lab InCube Co., Ltd., ensuring superior stability and sustained ingredient performance.
Clinical Results of PLLACUBE® Original
Clinically evaluated by the Human Skin Clinical Testing Center (2024), PLLACUBE® demonstrated remarkable improvements in multiple parameters, including hydration, elasticity, skin tone, and texture refinement — confirming its superior skin-regeneration performance.
48.95% improvement in surface skin hydration and 13.04% pore refinement observed after 3 weeks of use.
Study period: Jul. 23–Jul. 25, 2024 · Participants: 33 individuals · Study number: HM-P24-0335 · Testing Center: Human Skin Clinical Testing Center, Korea.
Advanced PLLA Particle Technology
Precision-engineered PLLA particles are carefully designed into a spherical shape, promoting smooth application and even distribution. The uniform particle size of 30–80 µm enhances product consistency and performance, contributing to a refined, professional-grade skincare experience.
FAQ
1. What is PLLACUBE Original?
1. What is PLLACUBE Original?
PLLACUBE Original is a 5th-generation Korean skinbooster containing Poly-L-Lactic Acid (PLLA), PDRN, Vitamin C, Glutathione, Hyaluronic Acid, and Houttuynia Cordata extract. It is designed for topical use with microneedling to support skin rejuvenation, firmness, and radiance.
2. What makes PLLACUBE different from other skinboosters?
2. What makes PLLACUBE different from other skinboosters?
PLLACUBE is a multi-functional skinbooster that uniquely combines PLLA, PDRN, Glutathione, Vitamin C, Hyaluronic Acid, and plant extract into a single freeze-dried formula. It features InCube™ Technology, which helps protect fragile actives from oxidation and degradation — ensuring maximum potency upon reconstitution.
3. How is PLLACUBE used in clinical settings?
3. How is PLLACUBE used in clinical settings?
PLLACUBE is designed for professional use across a range of advanced skin rejuvenation protocols, including microneedling, RF microneedling, infusion-focused facial treatments like JetPeel™ or CureJet™, and post-laser care such as CO₂ fractional or thulium laser procedures. Once reconstituted, the solution may be applied topically or paired with appropriate delivery systems to optimize absorption. Usage volume and dilution may vary based on clinical technique and goals.
4. Why is PLLACUBE used as an injection in some countries?
4. Why is PLLACUBE used as an injection in some countries?
PLLACUBE was originally developed as a topical-use cosmetic skinbooster, specifically designed to pair with microneedling treatments. It is manufactured as an injection-grade sterile product to meet the highest safety standards. In some countries, PLLACUBE is registered as a medical device, which allows its use via injection. However, in the North American market (Canada and the U.S.), PLLACUBE is officially classified and registered as a cosmetic product for topical application only.
5. Is PLLACUBE Health Canada/FDA approved?
5. Is PLLACUBE Health Canada/FDA approved?
Yes. PLLACUBE is registered with Health Canada as a cosmetic product for topical use. it is officially listed with the U.S. FDA as a cosmetic product under the FDA’s Cosmetic Product Listing Program (CPLP).
6. Can PLLACUBE be combined with other skinbooster?
6. Can PLLACUBE be combined with other skinbooster?
It is best applied as a standalone booster step due to its multi-ingredient formula.
7. Does PLLACUBE require refrigeration or special storage?
7. Does PLLACUBE require refrigeration or special storage?
No refrigeration is needed. PLLACUBE is freeze-dried for stability and should be stored in a cool, dry place away from direct sunlight. Reconstitute with distilled water or saline only when ready to use.
8. Is PLLACUBE safe for all skin types?
8. Is PLLACUBE safe for all skin types?
PLLACUBE is dermatologist-tested and shown to be non-irritating in clinical trials. It is suitable for most skin types, including normal to mildly sensitive skin. As with all professional-use products, a clinical evaluation is recommended before use.
Professional Treatment Protocol
Access our comprehensive guide for using PLLACUBE with microneedling, RF treatments, and post-laser care protocols.
View Protocol Guide