Conventional
Conventional PLLA
Irregular particle morphology may lead to uneven spread and inconsistent texture.
- Jagged/irregular edges
- Variable particle size distribution
Pioneering Korean 5th-Generation Skinbooster
PLLACUBE® Original
For Professional Use Only – A next-generation cosmetic formulation combining PLLA, PDRN, and advanced antioxidant complexes to help improve visible skin vitality and radiance.
Developed in Korea and trusted by over 100 dermatologist-led clinics across South Korea.
Enhanced with – Patented INCUBE™ Technology
- INCUBE™-C → Selective Ingredient Encapsulation
- INCUBE™-P → Environmental Protection System
- INCUBE™-R → Optimized Ingredient Release
Developed using patented proprietary technology (Patent No. 10-2488551), INCUBE™ delivers an advanced material protection platform for optimized ingredient stability and performance.
Clinical Results of PLLACUBE® Original
Clinically verified by the Human Skin Clinical Testing Center (2024), PLLACUBE® Original demonstrated measurable improvements in key skin parameters — including hydration, elasticity, brightness, and texture refinement — confirming its advanced skin-regeneration performance.
48.95% improvement in surface skin hydration and 13.04% pore refinement observed after 3 weeks of use.
Study period: Jul. 23–Jul. 25, 2024 · Participants: 33 individuals ·
Study number: HM-P24-0335 · Testing Center: Human Skin Clinical Testing Center, Korea.
*Based on a 3-week cosmetic study with 33 participants. Individual results may vary.
Key Ingredients of PLLACUBE® Original — All in One
Developed for professional use, PLLACUBE® Original combines Poly-L-Lactic Acid (PLLA) with
PDRN, Vitamin C, Glutathione, Houttuynia Cordata Extract, and Hyaluronic Acid
to deliver comprehensive support for visible skin rejuvenation. The multi-functional formulation helps improve
the look of firmness, brightness, hydration, and texture uniformity—offering a smoother, more refined complexion after treatment.
Within the formulation, Vitamin C and Glutathione are stabilized using the InCube™ technology platform
to help minimize oxidation and maintain ingredient freshness, supporting consistent quality with every application.
Ingredient diagram for illustrative purposes. Only Vitamin C and Glutathione are stabilized via the InCube™ platform. Learn more at Lab InCube Co., Ltd..
Advanced PLLA Particle Engineering
Near-spherical PLLA particles promote smooth application and even distribution. Precision sizing delivers consistent texture designed for professional performance.
Particle Size: 30–80 µm
Uniform, near-spherical morphology
Micrograph images are illustrative to highlight particle morphology differences.
FAQ
1. What is PLLACUBE Original?
1. What is PLLACUBE Original?
PLLACUBE Original is a 5th-generation Korean skinbooster containing Poly-L-Lactic Acid (PLLA), PDRN, Vitamin C, Glutathione, Hyaluronic Acid, and Houttuynia Cordata extract. It is designed for topical use with microneedling to support skin rejuvenation, firmness, and radiance.
2. What makes PLLACUBE different from other skinboosters?
2. What makes PLLACUBE different from other skinboosters?
PLLACUBE is a multi-functional skinbooster that uniquely combines PLLA, PDRN, Glutathione, Vitamin C, Hyaluronic Acid, and plant extract into a single freeze-dried formula. It features InCube™ Technology, which helps protect fragile actives from oxidation and degradation — ensuring maximum potency upon reconstitution.
3. How is PLLACUBE used in clinical settings?
3. How is PLLACUBE used in clinical settings?
PLLACUBE is designed for professional use across a range of advanced skin rejuvenation protocols, including microneedling, RF microneedling, infusion-focused facial treatments like JetPeel™ or CureJet™, and post-laser care such as CO₂ fractional or thulium laser procedures. Once reconstituted, the solution may be applied topically or paired with appropriate delivery systems to optimize absorption. Usage volume and dilution may vary based on clinical technique and goals.
4. Why is PLLACUBE used as an injection in some countries?
4. Why is PLLACUBE used as an injection in some countries?
PLLACUBE was originally developed as a topical-use cosmetic skinbooster, specifically designed to pair with microneedling treatments. It is manufactured as an injection-grade sterile product to meet the highest safety standards. In some countries, PLLACUBE is registered as a medical device, which allows its use via injection. However, in the North American market (Canada and the U.S.), PLLACUBE is officially classified and registered as a cosmetic product for topical application only.
5. Is PLLACUBE Health Canada/FDA approved?
5. Is PLLACUBE Health Canada/FDA approved?
Yes. PLLACUBE is registered with Health Canada as a cosmetic product for topical use. it is officially listed with the U.S. FDA as a cosmetic product under the FDA’s Cosmetic Product Listing Program (CPLP).
6. Can PLLACUBE be combined with other skinbooster?
6. Can PLLACUBE be combined with other skinbooster?
It is best applied as a standalone booster step due to its multi-ingredient formula.
7. Does PLLACUBE require refrigeration or special storage?
7. Does PLLACUBE require refrigeration or special storage?
No refrigeration is needed. PLLACUBE is freeze-dried for stability and should be stored in a cool, dry place away from direct sunlight. Reconstitute with distilled water or saline only when ready to use.
8. Is PLLACUBE safe for all skin types?
8. Is PLLACUBE safe for all skin types?
PLLACUBE is dermatologist-tested and shown to be non-irritating in clinical trials. It is suitable for most skin types, including normal to mildly sensitive skin. As with all professional-use products, a clinical evaluation is recommended before use.
Professional Treatment Protocol
Access our comprehensive guide for using PLLACUBE with microneedling, RF treatments, and post-laser care protocols.
View Protocol Guide
PLLACUBE - Boosters
