PLLACUBE Original professional cosmetic skinbooster

PLLA Vitamin C PDRN Houttuynia Glutathione HA

KOREA-DEVELOPED · PROFESSIONAL SKINBOOSTER

Fresh with InCube™ Technology.

Advanced Korean skin science powered by patented InCube™ Technology, developed for modern professional skincare.

Advanced Korean skin science powered by patented InCube™ Technology.

Explore PLLACUBE Get a free sample

Made in Korea Professional Use Shipped from Vancouver

THE SCIENCE INSIDE PLLACUBE

Six Actives.
One Advanced Formula.

Developed by LabInCube Korea, PLLACUBE Original combines PLLA with PDRN, Houttuynia Cordata Extract, Vitamin C, Glutathione and Hyaluronic Acid — powered by InCube™ materials technology for modern professional skincare.

30–80 μm Uniform PLLA particle range

≈ 4 min Ready to use — no long mixing

6 Actives One professional formula

Explore the Science

PLLA Poly-L-Lactic Acid

PDRN Sodium DNA

Houttuynia Cordata Extract

Hyaluronic Acid Sodium Hyaluronate

Glutathione Antioxidant active

Vitamin C Ethyl Ascorbyl Ether

PLLA PDRN Houttuynia HA Vitamin C Glutathione

ENGINEERED PLLA

Precision in
Every Particle.

PLLACUBE is engineered with controlled PLLA microspheres designed for uniformity in both particle size and morphology.

30–80 μm Controlled particle range

Near-Spherical Uniform morphology

SEM imaging highlights the distinct morphology of LabInCube engineered PLLA microspheres compared with a reference PLLA sample.

Discover PLLACUBE Technology

LABINCUBE PLLA 01

SEM image of LabInCube PLLA microspheres with uniform spherical morphology and 30 to 80 micrometer particle range

30–80 μm

REFERENCE PLLA 02

SEM reference image showing PLLA particles with irregular morphology

Engineered for a more controlled and consistent particle profile.

BUILT FOR PROFESSIONAL PRACTICE

Designed for the clinic.
Simple from start to finish.

PLLACUBE is designed to fit naturally into modern aesthetic practice — from preparation and storage to professional protocol guidance and partner support.

Professional clinic preparing PLLACUBE Original

CLINIC-READY WORKFLOW

Simple Preparation

Streamlined preparation designed for an efficient professional workflow.

Professional Protocols

Developed for professional skincare protocols in modern aesthetic practices.

Convenient Storage

Designed for convenient clinic inventory and preparation before reconstitution.

Clinic Partner Support

Professional onboarding, protocol guidance and support for PLLACUBE partner clinics.

Request a free sample & clinic access

Made in Korea Professional Use

CLINIC-READY WORKFLOW

PROFESSIONAL PRACTICE Designed around
the clinic workflow.

THE SCIENCE BEHIND PLLACUBE

From MOF Science
to Aesthetic Innovation.

PLLACUBE is developed by LabInCube Korea — translating advanced porous-material research into patented technology for professional cosmetic formulations.

MOF MATERIAL SCIENCE

2025 Nobel Prize
in Chemistry

The 2025 Nobel Prize in Chemistry recognized the development of metal–organic frameworks — the advanced porous-material field behind LabInCube's research foundation.

RESEARCH LINEAGE

From the Yaghi
Research Environment

LabInCube founder Prof. Kyung Min Choi previously conducted postdoctoral research in Prof. Omar M. Yaghi's laboratory at UC Berkeley.

PEER-REVIEWED RESEARCH

Academic Research
Collaboration

Published MOF studies include researchers affiliated with LabInCube, Seoul National University Bundang Hospital, Seoul National University and Sookmyung Women's University.

PROTECTED TECHNOLOGY

Patented
InCube™ Platform

InCube™ is supported by Korean Patent No. 10-2488551, covering a cyclodextrin-based metal–organic framework designed for controlled active-material delivery.

CLINICALLY EVALUATED FORMULATION

Science translated into measurable skin outcomes.

3 Weeks Cosmetic evaluation

Korea Human Skin Clinical Testing

PLLACUBE Finished-formula evaluation

SELECTED RESEARCH

Peer-reviewed publications

MOF · Biomaterials · Skin Research

ADVANCED HEALTHCARE MATERIALS · 2024

MOF hydrogel materials research (not a PLLACUBE study)

Sookmyung Women's University · Seoul National University Bundang Hospital · LabInCube Co., Ltd.

DOI 10.1002/adhm.202301679

IN VIVO · 2024

MOF silicone-patch materials research (not a PLLACUBE study)

Seoul National University Bundang Hospital · Seoul National University College of Medicine · LabInCube Co., Ltd.

DOI 10.21873/invivo.13430

RESEARCH AFFILIATIONS REPRESENTED IN PUBLISHED WORK

Sookmyung Women's University SNU Bundang Hospital Seoul National University LabInCube R&D

Measured on real skin

Results your clients can see — and you can explain.

A 3-week cosmetic study with 30 adults at a GCP-compliant skin research centre in Korea measured the change with instruments, not opinions.

+48.95%Surface hydration

−13.04%Pore volume

−7.58%Texture roughness

0.00Irritation index · 33 adults with sensitive skin

Before and 2 weeks after one in-clinic PLLACUBE facial — skin texture — Before / 2 weeks after one in-clinic PLLACUBE facial

Before and 2 weeks after one in-clinic PLLACUBE facial — redness and tone — Before / 2 weeks after one in-clinic PLLACUBE facial

Study: 3 weeks, 30 adults, microneedling with PLLACUBE, Korea 2024 (all changes vs. baseline, p < 0.001). Patch test is a separate study. Photos: unretouched clinic photos shared with client consent; PLLACUBE used as part of a professional facial protocol. Individual results vary.

Request a free sample vial See the full study

Built to sell, not just to ship

We don't just ship vials. We help you sell them.

~$300What many clinics charge for PLLACUBE as an add-on to an existing treatment

~$600A typical microneedling + PLLACUBE session price

1 vialPer full-face session · ready in about 4 minutes · no new device

Approved clinics get a launch kit with menu descriptions, client FAQs, Instagram captions and study images — plus protocol support from our Vancouver team. Wholesale prices are visible after login.

See it with your device Open a clinic account

Client prices are examples only; each clinic sets its own pricing.

The company behind the vial

Built by a materials-science company, not a label.

30+Countries where LabInCube's professional skinboosters are sold

IMCAS 2026PLLACUBE series — Innovation Awards finalist

ISO22716 cosmetics GMP · 9001 · 13485 quality systems

2026Prime Minister's Commendation, Korea · Series B investment

In Seoul, PLLACUBE sits on premium skinbooster menus at aesthetic clinics including branches of the Tox&Fill network and Cheongdam NB Clinic. Derma Essence Canada Ltd. is LabInCube's exclusive distribution partner for North America — supplying clinics across Canada from Vancouver.

Company facts from public reports and labincube.com. The 2025 Nobel Prize in Chemistry recognized MOF research (Kitagawa, Robson, Yaghi) — the field LabInCube works in — not PLLACUBE itself.

For clinics, med spas & aesthetic studios

Try PLLACUBE in your clinic — free.

One free sample vial for qualifying clinics, with the protocol guide. No minimum to start.

Request a free sample vial

Clinic brochure (PDF) · Protocol guide · Device protocols · Clinic FAQ

PLLACUBE Original

🔒 Registered Account Only

PiNk Vol. skinbooster vial containing 100mg (30mg PLLA), developed in Korea with Patent InCube Technology

PLLACUBE Original skinbooster vial containing 100mg (20mg PLLA), developed in Korea with Patent InCube Technology

Exclusive North American PLLACUBE Distributor

Discover Derma Essence Canada — the exclusive North American distributor of PLLACUBE, a professional cosmetic skinbooster developed by LabInCube Korea. Powered by patented InCube™ Technology, PLLACUBE is designed for professional use and formulated to support visible improvements in skin elasticity, hydration, and radiance. Each vial unites clinically evaluated ingredients including PLLA (Poly-L-Lactic Acid), PDRN, Vitamin C, Glutathione, Houttuynia Cordata extract, and Hyaluronic Acid—all stabilized for optimal skin performance.

Wholesale access for clinics, med spas & aesthetic studios Request a free sample & clinic access

Fresh with InCube™ Technology.

Six Actives.
One Advanced Formula.

Precision in
Every Particle.