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For professional use · Clinics, med spas & aesthetic studios

The professional skinbooster step for device treatments.

PLLACUBE is a freeze-dried, single-vial booster from Korea, prepared in about 4 minutes and added to the microneedling, RF, LaseMD, Clear + Brilliant and JetPeel sessions your clinic already offers.

FormatFreeze-dried vial, one per session
PreparationAbout 4 minutes
Key activesPLLA · PDRN · HA · Vit C · Glutathione
ApplicationTopical, with device treatments
PLLACUBE Original freeze-dried vial
IMCAS Innovation Awards 2026 — Finalist ISO 22716 · ISO 9001 · ISO 13485 Korean Patent 10-2488551 (InCube™) Health Canada cosmetic notification filed Exclusive North American distributor
Skin two weeks after one microneedling session with PLLACUBE

Two weeks after one microneedling session with PLLACUBE. Individual results vary.

Clinic economics

A premium add-on that is simple to price and stock.

~$300Typical client price as an add-on to a device session
~$600Microneedling + PLLACUBE as one combined session
~$1,200Client spend for a 4-session course, booked every 2–3 weeks
1 vialPer full-face session — every treatment has a fixed product cost

Client price examples reported by Canadian clinics; clinics set their own prices. Wholesale pricing is available after clinic approval.

Clinical data

Measured in a 3-week study.

Cosmetic use study, 30 adults, GCP-compliant skin research centre, Korea (2024). PLLACUBE applied with microneedling.

+48.95%

Skin surface hydration

−13.04%

Pore volume

−7.58%

Texture roughness

0.00

Irritation index — patch test, 33 sensitive-skin adults

Elasticity (R2) +3.82%. Individual results vary.

Protocol

Fits the devices you already own.

Add sterile water or saline, swirl and rest. One vial per full-face session. No refrigeration before mixing; refrigerate after and use within 48 hours.

Microneedling4 mL5 mL face + neck
RF microneedling4 mLMorpheus8-type sessions
LaseMD3.5 mLSame-session booster step
Clear + Brilliant3.5 mLSeries add-on
JetPeel5 mLNeedle-free infusion

Full steps in the protocol guide. Device names are trademarks of their respective owners.

Why PLLACUBE

Science, proof and a single authorized source.

Materials science

Developed by LabInCube, Seoul

A materials-science company specializing in MOFs — the field recognized by the 2025 Nobel Prize in Chemistry. Patented InCube™ keeps vitamin C and glutathione protected until mixing.

Used in Seoul

On Korean clinic menus

Offered in Seoul by clinics including Tox&Fill branches and Cheongdam NB Clinic, alongside the skinboosters Korean clients already know.

Authorized supply

Exclusive North American distributor

Derma Essence Canada Ltd. is the only authorized source of PLLACUBE in North America, shipping to Canadian clinics from Vancouver.

Getting started

Three steps to your first session.

Request your sample

Tell us about your clinic and the device treatments you offer. One complimentary vial per qualifying clinic.

Try it in a real session

The Clinic Starter Pack covers preparation, device volumes, menu copy and a client FAQ.

Order when you're ready

Once approved, clinic pricing opens at login. No minimum to start, shipped from Vancouver with tracking.

FAQ

Questions clinics ask.

More in the clinic FAQ.

Is PLLACUBE an injectable?

No. PLLACUBE is a professional cosmetic for topical use, applied as the booster step during device treatments such as microneedling, RF microneedling, LaseMD, Clear + Brilliant or JetPeel. It is not for injection.

Is it notified to Health Canada?

Yes. A Cosmetic Notification Form (CNF) has been filed with Health Canada for PLLACUBE.

Who can buy?

Clinics, med spas and aesthetic studios that offer device treatments, through an approved clinic account. Medical staff are not required.

Is there a minimum order?

No minimum to start. Orders ship from Vancouver with tracking, and clinic pricing is visible once your account is approved.

How long does one vial last?

One vial covers one full-face session. After mixing, refrigerate and use within 48 hours.

Evaluate PLLACUBE in your own treatment room.

One complimentary vial per qualifying clinic. No minimum order. Protocol and launch support included.