PLLACUBE Clinic FAQ
Straight answers for clinics, med spas and aesthetic studios. Don't see your question? Email info@derma-essence.com — a real person replies, usually the same business day.
Getting started
Who can buy PLLACUBE?
PLLACUBE is sold to professional businesses only — clinics, med spas and aesthetic studios that offer device treatments such as microneedling, RF microneedling, JetPeel, Clear + Brilliant, LaseMD or other laser facials. You don't need a physician on staff. We currently ship within Canada.
How do I open a clinic account?
Fill in the short Clinic Access form. We review it and email you once you're approved — then wholesale prices appear when you log in and you can order online.
Can I try it before I order?
Yes. We send one free sample vial to qualifying clinics, with the protocol guide. Request yours here or simply email us.
Is there a minimum order?
No minimum to start. You can order a single vial, a carton of 10 or five cartons, and the per-vial price drops as you buy more.
Why are prices hidden?
PLLACUBE is a professional-only product, so wholesale prices are shown to approved clinic accounts. Once you're approved, log in to see them.
In the treatment room
Which devices does PLLACUBE work with?
It's a topical booster step for the treatments you already offer: microneedling, RF microneedling (e.g. Morpheus8), JetPeel, Clear + Brilliant, LaseMD and other laser facials. See PLLACUBE with your devices for volumes per treatment.
How do I prepare a vial?
Add 3–5 mL of sterile distilled water or saline down the inside wall of the vial, swirl gently and let it rest. It reaches an even suspension in about 4 minutes. Full steps in the protocol guide.
How many vials per session?
One vial per full-face session.
How should I store it?
Unopened vials: a cool, dry place, no refrigeration needed. After mixing: refrigerate and use within 48 hours.
What course do clinics usually recommend?
Many clinics offer an initial series of 4 sessions about one week apart, then maintenance every 2–4 weeks. Adjust to your own protocol and each client.
Is PLLACUBE an injectable?
No. In Canada PLLACUBE is a professional cosmetic for topical use only. It is not for injection.
For your business
What do clinics charge clients?
Clinics set their own prices. As a reference, many offer PLLACUBE as an add-on of around $300, or around $600 as a full microneedling + PLLACUBE session.
Do you help with marketing?
Yes. Partner clinics get menu descriptions, client FAQs, Instagram captions and study images they can use, plus protocol support from our team in Vancouver.
What results can I share with clients?
In a 3-week cosmetic study with 30 adults (Korea, 2024), measured surface hydration increased by 48.95%, pore volume decreased by 13.04% and texture roughness decreased by 7.58%. A separate patch test on 33 adults with sensitive skin showed an irritation index of 0.00. Individual results vary.
About the product
Who makes PLLACUBE?
LabInCube, a Korean materials-science company founded in 2021 as a Sookmyung Women's University spin-off. LabInCube specializes in MOFs — the field recognized by the 2025 Nobel Prize in Chemistry. Derma Essence Canada Ltd. in Vancouver is the exclusive PLLACUBE distributor for North America.
Is PLLACUBE notified to Health Canada?
Yes. PLLACUBE is sold in Canada as a professional cosmetic, and a Cosmetic Notification Form (CNF) has been filed with Health Canada.
What's inside?
PLLA, PDRN (sodium DNA), hyaluronic acid, vitamin C, glutathione and houttuynia cordata extract, freeze-dried in one vial. Vitamin C and glutathione are protected by the patented InCube™ technology (Korean Patent 10-2488551).
Delivering the Key Ingredients for Healthy Skin in a Bottle for a Revitalized Complexion
Technical Key Points
LABINCUBE Co., Ltd., developing INCUBE™ technologies capable of selective and sustained release, and Capture and delivery for complex active ingredients.This advanced technology ensures reliable and effective delivery of functional ingredients.
PLLA Manufacturing Technology
The PLLA particles are formed into a spherical shape, which minimizes nodules and inflammatory response.
The particles have uniform sizes, ranging from 30 to 80 μm.
Conventional PLLA
LABINCUBE PLLA
INCUBE™ Storage Platform Technology
It protects functional materials during the manufacturing anddistribution process and exhibits long lasting results when used.
Ready to use — no long mixing
Instant hydration within 1 minute
PREMIUM COLLAGEN BOOSTER
Made with INCUBE™ Technology


